N-Isobutyl-3,4-methylenedioxy-trans-cinnamide with its unique chemical structure to affect many functional pathways is presented as an effective treatment of malaria, neurological disorders, androgenic disorders, rheumatoid arthritis, inflammatory bowel disease, vascular inflammation, hypertension, diabetes, obesity, fungal infections, bacterial infections, and cancer in adults and children; suitable pharmaceutical formulations are also disclosed for effective dosing.